Top 10 Best Pet Enzyme Cleaner [2025]

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Our team studied on 41933 reviews available online for Pet Enzyme Cleaner, chose the finest ones and prepared Pet Enzyme Cleaner Reviews for you. It was very difficult to shortlist the ideal Pet Enzyme Cleaner from thousands of products online. However, We tried to make sure that you get only the Best Pet Enzyme Cleaner from our suggestions. Check our listings-:

Best Pet Enzyme Cleaner
Disclaimer: As An Amazon Associate I Earn From Qualifying Purchases.

Comparison Chart for Best Pet Enzyme Cleaner

We found 41933 reviews when researching. We have considered users feedback on the Pet Enzyme Cleaner and our suggestions includes only the finest of them in this article.

NoProductScoreAction
1BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator - Enzymatic Stain Remover - Remove Dog Cat Urine Smell from Carpet9.8Buy On Amazon
2Simple Solution Pet Stain and Odor Remover - Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power - 32 Ounces9.4Buy On Amazon
3Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator - Urine Odor Remover - Pet Urine Enzyme Cleaner - Pet Stain and Odor Remover - Enzymatic Cleaner for Dog Urine and Cat Urine9.2Buy On Amazon
4Simple Solution Extreme Pet Stain and Odor Remover - Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power - 32 Ounces8.8Buy On Amazon
5Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for Home - Carpet Stain Remover for Cat and Dog Pee - Enzymatic Cat Urine Destroyer - Carpet Cleaner Spray8.4Buy On Amazon
6Pet Stain & Odor Miracle - Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit8.4Buy On Amazon
7BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator - Enzymatic Stain Remover - Remove Dog Cat Urine Smell from Carpet8.4Buy On Amazon
8AmazonCommercial Multi-Purpose Enzyme Cleaner8.2Buy On Amazon
9ANGRY ORANGE Enzyme Cleaner & Pet Stain Remover Spray - 32oz Pet Odor Eliminator for Home8.2Buy On Amazon
10Simple Green Bio Dog Active Stain & Odor Remover - Enzyme Cleaner & Stain Remover for Carpet8.2Buy On Amazon

Table Of Content:

1. BUBBAS Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator - Enzymatic Stain Remover - Remove Dog Cat Urine Smell from Carpet

  • BEST PROFESSIONAL GRADE CLEANING SOLUTION: Scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets.
  • PET STAIN AND ODOR MIRACLE: Bubba’s uses natural dormant enzymes that become active upon hitting that strong smelling cat pee, billions of enzymes destroy stains down to the carpet pad.
  • SATISFACTION GUARANTEED: Other pet odor enzyme sprays use active enzymes that are ineffective soon after you buy them.
  • CARPET & RUG INSTITUTE CERTIFIED: Our Pet Pee Cleaner and Enzymatic Odor Remover is a Top Rated pet stain & odor miracle.
  • MANY USES: Our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more.

2. Simple Solution Pet Stain and Odor Remover - Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power - 32 Ounces

  • REMOVES PET STAINS- Simple Solution Stain & Odor Remover is formulated to eliminate and neutralize tough dog and cat stains and odors like urine, feces, and vomit.
  • UNIQUE PRO-BACTERIA FORMULA – This stain and odor remover has a unique Pro-Bacteria and enzyme formula that eliminates stains and odors, and helps prevent repeat marking.
  • MULTIPLE USES – Safely removes dog and cat stains and odors from carpet, upholstery, bedding, fabric toys, clothing, and other water-safe surfaces in your home.
  • VERSATILE CLEANING – Our patented 3-in-1 nozzle sprayer gives you more options to tackle stains and odor: stream, foam, or mist.

3. Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator - Urine Odor Remover - Pet Urine Enzyme Cleaner - Pet Stain and Odor Remover - Enzymatic Cleaner for Dog Urine and Cat Urine

  • Scientifically Formulated Stain & Odor Eliminator: Removes the stain and stink from your pets
  • Enzyme Powered: Completely removes all pet stains and odors for urine, feces, vomit & drool.
  • Child & Pet Safe: Natural enzyme formula is the safest way to remove pet stains and odors.
  • Multi Surface: Use on carpet, wood, furniture, rugs, crates, upholstery, outdoor carpets etc.
  • 100% Guaranteed-Proudly Made In The USA: If you’re not 100% HAPPY, we will refund it in full

4. Simple Solution Extreme Pet Stain and Odor Remover - Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power - 32 Ounces

  • DESIGNED FOR THE TOUGHEST ODORS AND ORGANIC STAINS- Simple Solution pet Extreme Stain and Odor remover is three times stonger than our regular formula to eliminate tough dog and cat odors and stains.
  • PROFESSIONAL STRENGTH FORMULA – Extreme Stain and Odor Remover is a professional strength Pro-Bacteria and enzyme formula that breaks down and eliminates stains and odors.
  • SPECIFICALLY FOR PET ODORS AND ORGANIC STAINS – Safely and quickly removes dog and cat urine, feces, and vomit on carpet, upholstery, bedding, fabric toys, clothing, or other water-safe surfaces in your home.
  • NEW PATENTED MULTI-FUNCTIONAL SPRAYER – Now designed with a new patented 3-in-1 nozle sprayer (foam, mist, and stream).

5. Rocco & Roxie Stain & Odor Eliminator for Strong Odor – Enzyme-Powered Pet Odor Eliminator for Home – Carpet Stain Remover for Cat and Dog Pee – Enzymatic Cat Urine Destroyer – Carpet Cleaner Spray

  • ELIMINATES STAINS, ODORS AND RESIDUE If it’s gross, it’s gone.
  • CERTIFIED GENTLE AND SAFE Chlorine free and color safe.
  • EVERY SURFACE, EVERY TIME For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas — anywhere stains happen.
  • 100% SATISFACTION GUARANTEED An Amazon best seller for a reason.

6. Pet Stain & Odor Miracle – Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit

  • EASY CLEANUP – Pet Stain & Odor Miracle makes clean up fast and easy, so you can quickly return to having fun with your fur-baby.
  • INCREDIBLE VALUE – Pet Stain & Odor Miracle makes it very easy for you to clean every surface in your home – carpet, rug, hardwood, laminate, tile, concrete floor, furniture, mattress, leather, couch, pet beds, crates, litter box, car upholstery and mats.
  • HIGHEST QUALITY – All of Sunny & Honey’s products are made with the highest quality ingredients available, right here – in the beautiful USA.
  • NATURAL CLEANING POWER – Pet Stain & Odor Miracle was created with your furry kids in mind! This bio-enzymatic formula is biodegradable, non-toxic, and is scented with essential oils.
  • OUR PROMISE – If you are not 100% in LOVE with Pet Stain & Odor Miracle, send it back for a full refund.

7. BUBBAS Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator - Enzymatic Stain Remover - Remove Dog Cat Urine Smell from Carpet

  • BEST PROFESSIONAL GRADE CLEANING SOLUTION: Scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets.
  • PET STAIN AND ODOR MIRACLE: Bubba’s uses natural dormant enzymes that become active upon hitting that strong smelling cat pee, billions of enzymes destroy stains down to the carpet pad.
  • SATISFACTION GUARANTEED: Other pet odor enzyme sprays use active enzymes that are ineffective soon after you buy them.
  • CARPET & RUG INSTITUTE CERTIFIED: Our Pet Pee Cleaner and Enzymatic Odor Remover is a Top Rated pet stain & odor miracle.
  • MANY USES: Our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more.

8. AmazonCommercial Multi-Purpose Enzyme Cleaner

  • 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments.
  • Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results.
  • Ideal for commercial properties, retail, and hospitality
  • Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more.
  • Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent

9. ANGRY ORANGE Enzyme Cleaner & Pet Stain Remover Spray – 32oz Pet Odor Eliminator for Home

  • Enjoy all the furry love without the nasty messes! Our enzyme-active pet stain and odor remover can tackle any stubborn stains and foul smells, including pet urine, feces, and even vomit.
  • This isn’t just another pet spray that masks the bad odors and stains.
  • Discover an enzyme cleaner that can clean it all! Our solution is a pet cleaner for carpet, hardwood floors, tile, litter boxes, pillows, kennels, and more.
  • Made with enzymes and natural ingredients, this odor & urine remover for dogs and cats will leave a subtle orange / fresh scent behind without the use of harsh ingredients.
  • We care about making a great enzymatic cleaner with the strength to destroy messes, and keeping you and your pets happy.

10. Simple Green Bio Dog Active Stain & Odor Remover – Enzyme Cleaner & Stain Remover for Carpet

  • Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more.
  • Use on porous surfaces such as carpet, rugs, pet bedding, fabric, upholstery, clothing, curtains, Auto upholstery, crates, tile, finished wood, laminates, concrete and more.
  • Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
  • Safe for use around pets
  • Eliminates new, old and set-in stains

How To Choose The Best Pet Enzyme Cleaner

Does the thought of finding a great Pet Enzyme Cleaner stress you out? Has your mind been juggling between choices when it comes to buying Pet Enzyme Cleaner in general, specifically regarding which model to choose?
If that’s the case, know that you’re not alone. Many people find it tough to buy the perfect Pet Enzyme Cleaner for themselves. We understand the stress associated with the buying process!

Since you’re here, you are obviously curious about Pet Enzyme Cleaner. You’ve been bombarded with information, so you need to find a reputable source with credible options before you make any decisions on which product would be best for your needs.

There are many sources that’ll provide you with that information- buying guides or ratings websites, word-of-mouth testimonials from friends or family members, online forums where users share their personal experiences, product reviews specifically found all over the internet and YouTube channels. Only thorough research will ensure that you get the right product.

But that’s not always easy, right? That's why we've taken time to compile a list of the best Pet Enzyme Cleaner in today's market, on your behalf, so that there will be no more worries for you.

How did we come up with the list, you ask? How did we create this buying guide?

  • First, our algorithms collected as much information available about these products from trusted sources.
  • We employed both Artificial Intelligence and large data volume to validate all collected information.
  • Then our AI ranked them on their quality-to-price ratio using industry-standard criteria that let us pick the best Pet Enzyme Cleaner currently on the market!
The products aren’t chosen randomly. We consider several criteria before assembling a list. Some of the criteria are discussed below-

  1. Brand Value: What happens when you go for a not-so-reputable brand just because the price seems cheap? Well, the chance of getting a short-lasting product goes higher. That’s because the renowned brands have a reputation to maintain, others don’t.


Top Pet Enzyme Cleaner brands try to offer some unique features that make them stand out in the crowd. Thus hopefully, you’ll find one ideal product or another in our list.

  1. Features: You don’t need heaps of features, but useful ones. We look at the features that matter and choose the top Pet Enzyme Cleaner based on that.
  2. Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products of higher specifications, but with the right balance.
  3. Customer Ratings: The hundreds of customers using the Pet Enzyme Cleaner before you won’t say wrong, would they? Better ratings mean better service experienced by a good number of people.
  4. Customer Reviews: Like ratings, customer reviews give you actual and trustworthy information, coming from real-world consumers about the Pet Enzyme Cleaner they used.
  5. Seller Rank: Now, this is interesting! You don’t just need a good Pet Enzyme Cleaner, you need a product that is trendy and growing in sales. It serves two objectives. Firstly, the growing number of users indicates the product is good. Secondly, the manufacturers will hopefully provide better quality and after-sales service because of that growing number.
  6. Value For The Money: They say you get what you pay for. Cheap isn’t always good. But that doesn’t mean splashing tons of money on a flashy but underserving product is good either. We try to measure how much value for the money you can get from your Pet Enzyme Cleaner before putting them on the list.
  7. Durability: Durability and reliability go hand to hand. A robust and durable Pet Enzyme Cleaner will serve you for months and years to come.
  8. Availability: Products come and go, new products take the place of the old ones. Probably some new features were added, some necessary modifications were done. What’s the point of using a supposedly good Pet Enzyme Cleaner if that’s no longer continued by the manufacturer? We try to feature products that are up-to-date and sold by at least one reliable seller, if not several.
  9. Negative Ratings: Yes, we take that into consideration too! When we pick the top rated Pet Enzyme Cleaner on the market, the products that got mostly negative ratings get filtered and discarded.
These are the criteria we have chosen our Pet Enzyme Cleaner on. Does our process stop there? Heck, no! The most important thing that you should know about us is, we're always updating our website to provide timely and relevant information.

Since reader satisfaction is our utmost priority, we have a final layer of filtration. And that is you, the reader! If you find any Pet Enzyme Cleaner featured here Incorrect, irrelevant, not up to the mark, or simply outdated, please let us know. Your feedback is always welcome and we’ll try to promptly correct our list as per your reasonable suggestion.

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